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Wei Wei Selected Research

Phosphotransferases (Kinase)

10/2022Design, synthesis and biological evaluation of a series of novel pyrrolo[2,3-d]pyrimidin/pyrazolo[3,4-d]pyrimidin-4-amine derivatives as FGFRs-dominant multi-target receptor tyrosine kinase inhibitors for the treatment of gastric cancer.
2/2022Fasudil on Myocardial Injury in Rats with Myocardial Ischemia and Reperfusion through Rho-ROCK Signal Pathway.
11/2021Antitumor efficacy of CHMFL-KIT-110 solid dispersion in mouse xenograft models of human gastrointestinal stromal tumors.
7/2021Targeted inhibition of GRK2 kinase domain by CP-25 to reverse fibroblast-like synoviocytes dysfunction and improve collagen-induced arthritis in rats.
1/2021Vitamin C sensitizes BRAFV600E thyroid cancer to PLX4032 via inhibiting the feedback activation of MAPK/ERK signal by PLX4032.
1/2021Inhibition of yes-associated protein dephosphorylation prevents aggravated periodontitis with occlusal trauma.
11/2020Combined LIM kinase 1 and p21-Activated kinase 4 inhibitor treatment exhibits potent preclinical antitumor efficacy in breast cancer.
11/2020Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma.
11/2020EB virus-induced ATR activation accelerates nasopharyngeal carcinoma growth via M2-type macrophages polarization.
8/2020Red nucleus IL-6 mediates the maintenance of neuropathic pain by inducing the productions of TNF-α and IL-1β through the JAK2/STAT3 and ERK signaling pathways.
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Wei Wei Research Topics

Disease

592Neoplasms (Cancer)
12/2022 - 08/2003
119Hepatocellular Carcinoma (Hepatoma)
10/2022 - 05/2003
104Inflammation (Inflammations)
07/2022 - 07/2005
102Breast Neoplasms (Breast Cancer)
04/2022 - 05/2008
90Neoplasm Metastasis (Metastasis)
05/2022 - 07/2004
82Infections
12/2022 - 12/2006
60Experimental Arthritis
08/2022 - 09/2002
60Rheumatoid Arthritis
07/2022 - 07/2008
49Arthritis (Polyarthritis)
07/2022 - 09/2002
43Carcinogenesis
12/2022 - 11/2006
42Fibrosis (Cirrhosis)
03/2022 - 04/2005
36Pain (Aches)
09/2022 - 03/2006
34COVID-19
08/2022 - 01/2020
33Prostatic Neoplasms (Prostate Cancer)
08/2022 - 01/2015
32Stomach Neoplasms (Stomach Cancer)
10/2022 - 05/2010
32Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 02/2009
29Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2022 - 01/2007
29Necrosis
01/2021 - 10/2002
28Lung Neoplasms (Lung Cancer)
10/2022 - 01/2009
28Carcinoma (Carcinomatosis)
04/2022 - 08/2003
28Alzheimer Disease (Alzheimer's Disease)
12/2021 - 01/2005
27Colorectal Neoplasms (Colorectal Cancer)
06/2022 - 05/2007
27Wounds and Injuries (Trauma)
01/2022 - 03/2007
26Hypoxia (Hypoxemia)
03/2022 - 01/2005
26Body Weight (Weight, Body)
01/2022 - 05/2006
25Type 2 Diabetes Mellitus (MODY)
08/2022 - 01/2011
24Autoimmune Diseases (Autoimmune Disease)
08/2022 - 01/2009
22Melanoma (Melanoma, Malignant)
02/2021 - 08/2012
20Pancreatic Neoplasms (Pancreatic Cancer)
01/2021 - 05/2013
19Insulin Resistance
06/2022 - 12/2009
18Glioma (Gliomas)
02/2022 - 02/2008
18Obesity
01/2022 - 03/2011
18Multiple Myeloma
01/2021 - 06/2010
17Leukemia
12/2022 - 08/2008
17Hypothyroidism
12/2021 - 03/2010
16Cardiovascular Diseases (Cardiovascular Disease)
08/2022 - 12/2009
16Liver Cirrhosis (Hepatic Cirrhosis)
07/2021 - 07/2004
16Lymphatic Metastasis
06/2021 - 01/2007
15Atherosclerosis
05/2022 - 06/2003
14Hemorrhage
01/2022 - 07/2007
14Stroke (Strokes)
11/2021 - 07/2003
14Triple Negative Breast Neoplasms
06/2021 - 11/2013
13Dyspepsia (Indigestion)
06/2022 - 06/2007
13Mitochondrial Diseases (Mitochondrial Disease)
05/2022 - 02/2009
13Sepsis (Septicemia)
05/2022 - 03/2005
13Glioblastoma (Glioblastoma Multiforme)
01/2022 - 01/2012
13Atrial Fibrillation
01/2021 - 01/2009

Drug/Important Bio-Agent (IBA)

199Proteins (Proteins, Gene)FDA Link
12/2022 - 01/2005
106Biomarkers (Surrogate Marker)IBA
12/2022 - 01/2007
98Pharmaceutical PreparationsIBA
08/2022 - 10/2007
70MicroRNAs (MicroRNA)IBA
05/2022 - 08/2008
60Biological ProductsIBA
12/2022 - 08/2003
53CytokinesIBA
01/2022 - 07/2005
47Therapeutic UsesIBA
05/2022 - 11/2004
45Messenger RNA (mRNA)IBA
05/2022 - 07/2004
31Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2022 - 10/2002
30Glucose (Dextrose)FDA LinkGeneric
06/2022 - 05/2007
30Long Noncoding RNAIBA
05/2022 - 01/2016
30Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2022 - 06/2002
27Peptides (Polypeptides)IBA
05/2022 - 01/2005
27AntigensIBA
05/2022 - 03/2006
26DNA (Deoxyribonucleic Acid)IBA
12/2022 - 07/2009
26EnzymesIBA
06/2022 - 11/2008
25RNA (Ribonucleic Acid)IBA
01/2022 - 07/2005
24Indicators and Reagents (Reagents)IBA
05/2022 - 07/2010
24CollagenIBA
03/2022 - 04/2005
24Small Interfering RNA (siRNA)IBA
11/2021 - 09/2010
23Reactive Oxygen Species (Oxygen Radicals)IBA
05/2022 - 12/2006
23MelatoninIBA
12/2021 - 09/2002
22CateninsIBA
03/2022 - 12/2011
22IodineIBA
01/2022 - 03/2010
21Interleukin-6 (Interleukin 6)IBA
05/2022 - 04/2006
21AntibodiesIBA
01/2022 - 11/2007
21peoniflorinIBA
12/2021 - 04/2006
20Phosphotransferases (Kinase)IBA
10/2022 - 04/2013
20LigandsIBA
04/2022 - 08/2008
20LipopolysaccharidesIBA
01/2022 - 12/2005
19Cisplatin (Platino)FDA LinkGeneric
02/2021 - 02/2005
18LipidsIBA
01/2022 - 06/2003
17Methotrexate (Mexate)FDA LinkGeneric
06/2022 - 07/2008
17Oxygen (Dioxygen)IBA
06/2022 - 01/2005
16Paclitaxel (Taxol)FDA LinkGeneric
05/2022 - 03/2011
16GlucosidesIBA
01/2019 - 04/2003
15Transcription Factors (Transcription Factor)IBA
12/2022 - 10/2005
15Estrogen ReceptorsIBA
10/2021 - 06/2014
14ErbB Receptors (EGF Receptor)IBA
10/2022 - 07/2004
14Immune Checkpoint InhibitorsIBA
05/2022 - 12/2017
14VaccinesIBA
01/2022 - 04/2009
14AlbuminsIBA
09/2021 - 11/2008
14Doxorubicin (Adriamycin)FDA LinkGeneric
01/2020 - 01/2007
13Caspase 3 (Caspase-3)IBA
01/2022 - 03/2005
13Hormones (Hormone)IBA
01/2021 - 05/2008
12Fluorouracil (Carac)FDA LinkGeneric
10/2022 - 01/2007
12Oxaliplatin (Eloxatin)FDA LinkGeneric
10/2022 - 06/2010

Therapy/Procedure

226Therapeutics
12/2022 - 08/2003
85Drug Therapy (Chemotherapy)
12/2022 - 02/2007
41Radiotherapy
07/2022 - 04/2008
38Immunotherapy
12/2022 - 03/2009
17Neoadjuvant Therapy
01/2022 - 01/2013
16Aftercare (After-Treatment)
04/2022 - 11/2013